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Our specialist examine at the labrotary

Who we are

The Leading Research Institute specialized in Fatty Liver Disease. 

Houston Research Institute is dedicated to conducting clinical trials in the areas of Hepatology and Gastroenterology, with a special focus on fatty liver disease. We pride ourselves on conducting high quality research as a complement to the medical care that our volunteers receive from their routine care center.

We are constantly innovating our strategies and methods to find the most efficient treatment and diagnostic methods for developing better patient outcomes. Our clinical research team are licensed and certified individuals in the healthcare and clinical research profession. Our objective is to implement subject safety while participating in research and the efficient conduct of clinical trials. Our research site ensures that data management, clinical laboratory, information technology, quality assurance, full time staff, recruitment and retention, contracts and budget, regulatory affairs, and pharmacy are continuously updated.

Your trusted source for clinical research in Houston

Utilizing cutting edge clinical research as an option for furthering patient care and giving you access to early, safe and promising new therapies and diagnostic tests.

Meet Dr. Mazen Noureddin - Fatty Liver Specialist

Dr. Mazen Noureddin - Medical Director and Fatty Liver Specialist at Houston Research Institute at Houston L

Mazen Noureddin, MD, MHSc

Medical Director

“Life isn't about finding yourself. Life is about creating yourself.”

Mazen Noureddin, MD, MHSc, was the founding director of the Fatty Liver Program at Cedars-Sinai Medical Center (currently ranked #2 in GI and GI surgery per US News). He recently relocated to Texas from California to establish a state-of-the-art Houston Research Institute.   Dr. Noureddin did his internal medicine residency at the University of Southern California (USC) and then moved to the National Institutes of Health (NIH), where he enrolled in a three-year hepatology fellowship at the Liver Diseases Branch of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). There, he finished the NIH/Duke University Master of Health Sciences in Clinical Research program. After completing his NIH fellowship, he completed a gastroenterology fellowship at the University of California, San Diego (UCSD), where he was a T32 NIH fellow. He then joined the University of Southern California (USC) as an Assistant Professor of Clinical Medicine in 2013. He was then recruited to Cedars-Sinai Medical Center in 2015 to establish its new fatty liver program.

Dr. Noureddin is internationally known for his research in the area of NAFLD/NASH and NASH related cirrhosis. He conducted more than 40 investigational clinical studies of novel treatments for NASH. He is an expert in non-invasive testing and biomarkers of NASH and cirrhosis. He has published in all these areas and has been invited to consensus panels on these topics by multiple international societies including the American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of Liver Diseases (EASL). He has given invited lectures on NAFLD/NASH at national and international society meetings and serves on several steering committees/advisory boards for industry. He is the vice chair of the AASLD NASH special interest group (will be chairing the group in 2023) and serves on the editorial board for major GI journals including “Gastroenterology”, “Hepatology” and  “Clinical Gastroenterology and Hepatology (CGH)”. He is one of the new Associate Editors of “Clinical Gastroenterology and Hepatology (CGH)”. He is funded by the National Cancer Institute and has served as a reviewer on NIH study sections. Dr. Noureddin has published in many journals including: The Lancet, Science Trinational Medicine, Journal of Hepatology, Journal of Clinical Investigation, Gastroenterology, Hepatology, Clinical Gastroenterology and Hepatology and others

Take a look behind the scenes at Houston Research Institute

  • Dedicated patient rooms for research activities

  • In-house dedicated research laboratory for processing and shipping

  • On-Site FibroScan ®

  • Wireless temperature monitoring system for ambient, cold and frozen storage for biological samples and drug supply

  • Multilingual clinical research staff

  • Monitoring Room

Currently Enrolling 

  • Non-alcoholic fatty liver disease (NAFLD)

  • Non-alcoholic steatohepatitis (NASH)

  • Obesity

  • Hepatitis B and C

  • Primary biliary cholangitis (PBC)

  • Primary sclerosis cholangitis (PSC)

  • Portal hypertension

  • Cirrhosis

  • Other hepatic and GI diseases and conditions

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